Table 7.

Pathways enriched for target genes of 11 highly correlated miRNAs in MCI

# KEGG pathway	p-value	#genes	#miRNAs
1 MAPK signaling pathway (hsa04010)	1.81 ×10−13	79	11
2 Endocytosis (hsa04144)	5.43 ×10−12	63	10
3 TGF-beta signaling pathway (hsa04350)	5.43 ×10−12	31	10
4 PI3K-Akt signaling pathway (hsa04151)	3.88 ×10−10	91	11
5 Pathways in cancer (hsa05200)	4.62 ×10−10	92	11
6 Neurotrophin signaling pathway (hsa04722)	5.66 ×10−8	38	11
7 Prostate cancer (hsa05215)	6.03 ×10−8	30	10
8 Ubiquitin mediated proteolysis (hsa04120)	1.37 ×10−7	41	11
9 ErbB signaling pathway (hsa04012)	5.11 ×10−7	29	10
10 Hepatitis B (hsa05161)	6.96 ×10−7	41	11