Table 10. Stability of antimicrobial activity of liposomes with co-encapsulated lysozyme and plant extracts during long-term storage compared with non-encapsulated lysozyme (γ=1 mg/mL).
| Material | t/day | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Acidic food | Food containing water | Food containing alcohol | Fatty food | |||||||||
| 0 | 7 | 28 | 7 | 28 | 7 | 28 | 7 | 28 | ||||
| d(inhibition zone)/mm | ||||||||||||
| Bacillus subtilis | ||||||||||||
| thyme | 2.5hi | 2.0i | 1.3j | 6.2f | 4.1gh | 5.6fg | 3.2h | 5.9f | 4.0gh | |||
| sage | 3.8gh | 3.2h | 2.8hi | 7.1ef | 4.8g | 3.9gh | 2.1i | 4.9g | 2.8hi | |||
| lavender | 2.0i | 1.5j | 1.2j | 4.5g | 2.1i | 2.9h | 2.1i | 3.9gh | 2.1i | |||
| elderberry | 4.3gh | 4.1gh | 3.0h | 5.8f | 3.8gh | 3.5h | 2.4i | 2.8hi | 1.8ij | |||
| marjoram | 1.3j | 1.0j | 0.8jk | 4.1gh | 3.5h | 4.2gh | 2.9h | 3.4h | 1.7ij | |||
| lysozyme | 19.0a | 5.0g | 2.0i | 8.0e | 6.0f | 5.0g | 4.0gh | 4.0gh | 3.0h | |||
| Micrococcus luteus | ||||||||||||
| thyme | 5.0g | 4.0gh | 2.7hi | 7.1ef | 2.4i | 5.6fg | 4.4gh | 6.1f | 3.8gh | |||
| sage | 8.2e | 7.0ef | 5.2fg | 5.8f | 4.2gh | 8.4e | 7.2ef | 6.2f | 2.8hi | |||
| lavender | 2.5hi | 1.5j | 0.8jk | 4.5g | 2.2i | 4.4gh | 3.8gh | 3.2h | 3.0h | |||
| elderberry | 5.5fg | 4.2gh | 2.5hi | 2.8hi | 1.2j | 4.9g | 4.5g | 4.0gh | 1.1j | |||
| marjoram | 4.0gh | 3.0h | 2.5hi | 1.8ij | 0.9j | 3.9gh | 2.2i | 2.0i | 1.2j | |||
| lysozyme | 17.0b | 5.2fg | 1.8ij | 7.5ef | 6.5f | 8.0e | 6.0f | 5.1fg | 3.2h | |||
| Escherichia coli | ||||||||||||
| thyme | 7.0ef | 6.5f | 4.4gh | 6.5f | 3.8gh | 6.9f | 2.8hi | 5.9f | 3.6gh | |||
| sage | 5.2fg | 4.5g | 3.5h | 5.9f | 4.4gh | 6.2f | 3.4h | 6.2f | 5.1fg | |||
| lavender | 10.0c | 9.0d | 5.8f | 3.2h | 1.0j | 4.1gh | 2.1i | 2.6hi | 2.0i | |||
| elderberry | 7.5ef | 6.2f | 2.6hi | 2.6hi | 0.5k | 3.1h | 1.1j | 2.2i | 1.1j | |||
| marjoram | 4.5g | 3.5h | 1.8ij | 1.9i | 1.0j | 3.1h | 0.5k | 1.8ij | 0.0k | |||
| lysozyme | 6.0f | 2.0i | 0.0k | 3.0h | 3.0h | 2.0i | 1.0j | 3.0h | 1.0j | |||
Antimicrobial activity was measured by well diffusion assay. Inhibition zones represent the average values of two measurements. Mean values with different letters in superscript are statistically different (p<0.05)