Table 1. Sensory abilities, neurological reflexes, neuromuscular strength, and motor functions of control and Y1-/- mice.
Observation | Control | Y1-/- |
---|---|---|
Sensory abilities | ||
Startle response | Normal | Normal |
Visual cliff and strange stimulus | Normal | Normal |
Olfaction (hidden cookie) | Normal | Normal |
Neurological reflexes | ||
Balance ability and righting | Normal | Normal |
Eye blink and ear twitch | Normal | Normal |
Whisker-orienting | Normal | Normal |
Constriction and dilatation | Normal | Normal |
Neuromuscular strength | ||
Wire-hang test, s | 58.3 | 47.4 |
Motor function tests | ||
Beam walking (different dimensions), s | 74.0 | 52.5 |
Pole, s | 83.7 | 79.2 |
Accelerod (day 1-4), s | 224.0 | 263.4 |
Footprint | ||
Stride length, cm | 5.7 | 5.7 |
Hind/front base width, cm | 3.3 | 3.4 |
Distance front/hind footprint, cm | 1.3 | 1.3 |
Existence/occurrence of sensory abilities/reflexes is defined as “normal.” For the different neuromuscular strength and motor functions tasks, means are presented. (n = 9-10 mice.)