Table 1.
Summary statistics for demographic characteristics, repeated serum samples of selected PBDEs, and reproductive function tests in adult men, by sampling round (27 men, 76 samples).
| Characteristic | Round 1 (24 samples) | Round 2 (27 samples) | Round 3 (25 samples) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| GM | (GSD) | Range | GM | (GSD) | Range | GM | (GSD) | Range | |
| Demographics | |||||||||
| Age (years)a | 41.0 | (13.8) | 25–66 | 41.3 | (13.3) | 25–66 | 41.8 | (12.6) | 26–67 |
| BMI (mg/kg2)a | 25.3 | (3.6) | 20–38 | 25.3 | (3.5) | 20–38 | 25.1 | (3.6) | 20–38 |
| Total Lipidsa | 644.8 | (118) | 448–864 | 630.4 | (123) | 396–912 | 632.2 | (124) | 328–843 |
| PBDEs (ng/g lipid) | |||||||||
| BDE−28b | 0.51 | (2.5) | 0.15–2.8 | 0.62 | (2.5) | 0.15–5.1 | 0.5 | (2.3) | 0.15–3.6 |
| BDE−47b | 9.4 | (3.0) | 1.7–151 | 9.9 | (2.8) | 1.4–149.0 | 8.2 | (2.5) | 1.8–98.9 |
| BDE−99b | 1.9 | (3.0) | 0.25–43.5 | 1.9 | (3.0) | 0.25–34.1 | 1.6 | (2.5) | 0.30–20.1 |
| BDE−100b | 1.8 | (4.0) | 0.20–42.4 | 2 | (3.5) | 0.25–44.1 | 1.5 | (3.0) | 0.30–35.2 |
| BDE−153b | 8.6 | (3.1) | 1.6–96.7 | 8.6 | (3.1) | 1.7–94.7 | 6.8 | (2.8) | 1.5–55.2 |
| ∑PBDEsb | 25.5 | (2.8) | 5.8–294.0 | 25.5 | (2.6) | 6.55–293.5 | 21.1 | (2.3) | 5.85–211.1 |
| Reproductive Testsc | |||||||||
| Total T (ng/dl)a | 627.6 | (254) | 310–1182 | 633.2 | (200) | 285.4–1031 | 470.1 | (159) | 199.4–795.4 |
| Free T (pg/ml)a | 109.1 | (34.2) | 59.7–167.1 | 109.6 | (36.8) | 50.4–197.5 | 83.8 | (29.5) | 34.6–149.1 |
| Inhibin-B (pg/mL)a | 189.8 | (67.2) | 16.6–320.9 | 183.7 | (75.8) | 18.5–423.3 | 190.1 | (83.6) | 17.2–441.1 |
| FSH (IU/L) | 3.12 | (1.73) | 1.40–17.6 | 3.21 | (1.76) | 1.32–19.6 | 3.29 | (1.81) | 1.41–19.6 |
| LH (U/L) | 4.5 | (1.58) | 2.12–12.57 | 3.93 | (1.53) | 1.97–13.9 | 4.39 | (1.60) | 1.82–13.7 |
| Prolactin (ng/mL) | 4.25 | (1.45) | 2.05–7.28 | 4.97 | (1.49) | 2.39–9.34 | 5.15 | (1.43) | 2.40–9.82 |
| SHBG (nmol/L) | 42.7 | (1.60) | 14.0–83.8 | 45.3 | (1.59) | 12.7–92.7 | 40.5 | (1.56) | 12.2–76.4 |
| Inhibin-B/FSH | 63.0 | (52.6) | 0.94–188 | 64.1 | (56.8) | 0.95–258 | 65.8 | (57.1) | 0.88–238 |
| FAI | 1360 | (104) | 738–3850 | 1330 | (149) | 685–3180 | 1090 | (151) | 520–2100 |
Abbreviations: BMI: body mass index, FAI: free androgen index, FSH: follicular stimulating hormone, GM: geometric mean, GSD: geometric standard deviation, LH: luteinizing hormone, SHBG: sex hormone binding globulin, T: testosterone.
a
Means and standard deviations presented.
b
Detection rates presented in Supplemental Table, S2.
c
Normal Reference Range for adult males in good health: testosterone = 300–1000 ng/dL, free testosterone = 50–200 pg/mL inhibin-B = elevated if above 399 pg/mL, FSH = 0.60–9.98 IU/L, LH = 1.0–8.4 U/L, SHBG = 12.9–61.7 nmol/L.