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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Adv Healthc Mater. 2016 Sep 26;5(21):2751–2757. doi: 10.1002/adhm.201600820

Figure 3.

Figure 3

PTK-UR scaffolds loaded with PHD2-siNPs (A) significantly decrease PHD2 mRNA within the wound tissue scaffolds compared to NT and SCR-siNP implants, leading to (B) increased HIF-1α and (C) increased VEGF protein levels compared to SCR-siNP implants at day 4 post-implantation (mean ± SEM, n = 6 independent animals, *p<0.05).