Table 1.
Data on subjects aged 45+ years with a diagnosis of atrial fibrillation in primary care from 1 January 2001 to 31 December 2007, and patients with an ischemic stroke (IS)
| All (n=11,517) | With IS (n=1,465) | |||
|---|---|---|---|---|
| Women n=5,248 |
Men n=6,269 |
Women n=768 |
Men n=697 |
|
| Age (years), mean (SD) | 76.9 (9.3) | 71.8 (10.2) | 79.0 (8.0) | 74.7 (8.8) |
| Age group (years) | n (%) | n (%) | n (%) | n (%) |
| 45–54 | 105 (2.0) | 363 (5.8) | 6 (0.8) | 17 (2.4) |
| 55–64 | 499 (9.5) | 1,184 (18.9) | 43 (5.6) | 79 (11.3) |
| 65–74 | 1,199 (22.9) | 1,951 (31.1) | 137 (17.8) | 213 (30.6) |
| 75–84 | 2,343 (44.7) | 2,162 (34.5) | 381 (49.6) | 298 (42.8) |
| 85+ | 1,102 (21.0) | 609 (9.7) | 201 (26.2) | 90 (12.9) |
| Neighbourhood SES | ||||
| High | 1,810 (34.5) | 2,508 (40.0) | 396 (51.6) | 318 (45.6) |
| Middle | 2,508 (49.2) | 2,866 (45.7) | 265 (34.5) | 281 (40.3) |
| Low | 858 (16.4) | 895 (14.3) | 107 (13.9) | 98 (14.1) |
| Marital status | ||||
| Married | 1,552 (29.7) | 3,705 (60.1) | 188 (24.6) | 405 (58.3) |
| Unmarried | 374 (7.2) | 606 (9.7) | 50 (6.5) | 53 (7.6) |
| Divorced | 739 (14.2) | 942 (15.1) | 91 (11.9) | 96 (13.8) |
| Widowed | 2,558 (49.0) | 956 (15.2) | 435 (56.9) | 141 (20.3) |
| Educational level | ||||
| Compulsory school | 2,407 (52.2) | 2,340 (39.4) | 372 (57.2) | 251 (38.1) |
| Secondary school | 1,527 (33.1) | 2,234 (37.6) | 200 (30.8) | 266 (40.4) |
| College/university | 680 (14.7) | 1,369 (23.0) | 78 (12.0) | 142 (21.6) |
| AF-related disease | ||||
| Hypertension | 2,553 (48.7) | 2,591 (41.3) | 387 (50.4) | 324 (46.5) |
| Coronary heart disease | 1,098 (20.9) | 1,260 (20.1) | 155 (20.2) | 157 (22.5) |
| Congestive heart failure | 1,084 (20.7) | 1,082 (17.3) | 157 (20.4) | 121 (17.4) |
| Diabetes mellitus | 1,021 (19.5) | 1,231 (19.6) | 134 (17.5) | 181 (26.0) |
| Drugs | ||||
| Ever-present warfarin | 2461 (46.9) | 3485 (55.6) | 354 (46.1) | 397 (57.0) |
| Warfarin ITT | 2310 (44.0) | 3306 (52.7) | 236 (30.7) | 251 (36.0) |
| Warfarin PP | 1768 (33.7) | 2508 (40.0) | 160 (20.8) | 148 (21.2) |
SES denotes “socio-economic status”.
ITT denotes “intention-to-treat”: prescription before the years of first stroke, or present among subjects not experiencing a stroke.
PP denotes “per-protocol” (“PP”): prescription the year before and the year of first stroke, or present among subjects not experiencing a stroke if present at least during three years, of at least 50% of actual years after first recorded year of AF, or during both 2006 and 2007.