FIG. 6.

Antibody to lipoarabinomannan during treatment of tuberculosis. The relative increase in antibody titer appeared greater for the purified lipoarabinomannan than for antibody, as determined by the competition assay. An example of plotting the reciprocal of the absorbance against the serum dilution is given, from which the affinity of the serum was calculated. The third graph suggests that antibody titers follow the calculated “affinity” in a linear fashion, consistent with an absence of affinity maturation during treatment.