TABLE 1.
Frequency of positive titers of antibodies to six epitopes restricted to M. tuberculosis during treatment
| Epitope | Antigen | No. of positive titersa
|
||||||
|---|---|---|---|---|---|---|---|---|
| S+C+
|
S−C+
|
S−C−
|
||||||
| Day 0 | Day 7 | >Day 7 | Day 0 | >Day 7 | Day 0 | >Day 7 | ||
| TB23 | 19 kDa | 13 | 16 | 27 | 0 | 0 | 0 | 1 |
| TB68 | 16 kDa | 14 | 19 | 29 | 1 | 3 | 1 | 3 |
| TB71 | 38 kDa | 22 | 25 | 35 | 1 | 2 | 1 | 4 |
| TB72 | 38 kDa | 27 | 28 | 35 | 1 | 4 | 1 | 4 |
| TB78 | hsp65 | 19 | 20 | 33 | 1 | 1 | 2 | 4 |
| ML34 | LAMb | 19 | 22 | 32 | 2 | 2 | 2 | 2 |
| Any | 35 | 36 | 38 | 2 | 4 | 3 | 6 | |
a
S+C+, smear- and culture-positive pulmonary tuberculosis (n = 40); S−C+, smear-negative, culture-positive pulmonary tuberculosis (n = 7); S−C−, smear- and culture-negative pulmonary tuberculosis with response to treatment (n = 7).
b
LAM, lipoarabinomannan.