Table 2.
Subjective effects by dose, session, and personality
| VAS Variables | SS | Imp | Dose | SS × Dose | Imp × Dose | Dose × Time | SS × Dose × Time | Imp × Dose × Time |
|---|---|---|---|---|---|---|---|---|
| Visual Analog Scale | ||||||||
| Anxious | 1.86 | .55 | 5.97** | .17 | .13 | 1.45 | .46 | .50 |
| Any Effect | .86 | 1.31 | 23.98*** | 1.31 | .68 | 18.37*** | 2.54* | 2.78* |
| Bad Effect | .46 | 4.23* | 2.95† | .44 | .02 | 3.04** | .92 | .51 |
| Good Effect | .25 | .76 | 17.80*** | 2.68† | .43 | 13.39*** | 4.14*** | 3.16** |
| High | .57 | .66 | 8.25*** | 1.14 | .15 | 4.73*** | 1.04 | .22 |
| Impaired | .01 | .44 | 2.02 | .18 | .78 | 2.57* | 1.36 | 1.18 |
| Improved | .15 | .20 | 17.92*** | .92 | .28 | 6.76*** | 1.82 | .96 |
| Like Drug | 6.03* | 7.01** | 20.98*** | 3.02† | .44 | 3.80** | .81 | 1.13 |
| Take Again | 2.70 | 2.35 | 6.95** | 1.81 | .10 | 3.30** | 1.33 | .63 |
| Adjective Rating Scale | ||||||||
| Stimulated | .24 | .25 | 12.79*** | .99 | .87 | 11.89*** | 1.44 | 1.54 |
| Sedated | .01 | .58 | 11.27*** | .17 | .04 | 4.42*** | .63 | 1.08 |
| Modified Progressive Ratio Task | ||||||||
| Capsules Earned | .13 | .62 | 1.17 | 5.27** | 1.45 | -- | -- | -- |
| Cardiovascular Measures | ||||||||
| Heart Rate | .06 | .01 | 14.14*** | 1.34 | .21 | 11.03*** | 3.01** | .91 |
| Diastolic Blood Pressure | 1.23 | .60 | 12.88*** | .39 | 1.31 | 3.84** | 1.48 | .26 |
| Systolic Blood Pressure | .62 | .12 | 28.17*** | 2.5 | 1.51 | 4.46*** | 1.76 | .95 |
All values displayed are F values. VAS= Visual Analog Scale, SS=sensation-seeking, Imp=impulsivity
†
p≤10
*
p≤.05
**
p≤.01
***
p≤.001