Table 2.

Multivariable linear models examining association of cognitive performance (GDS and T scores) with HIV and Toxoplasmosis using 2-way ANOVA analysis. Significant effects of either HIV or Toxoplasma are shown in the last column for each cognitive outcome. Interaction between HIV and Toxoplasmosis were not significant (results are not shown).

Cognitive domain	HIV-/Toxo- (n=33)	HIV-/Toxo+ (n=18)	HIV+/Toxo- (n=131)	HIV+/Toxo+ (n=63)	Significant Effects
GDS	0.20 (0.21)	0.29 (0.31)	0.44 (0.44)	0.59 (0.48)	HIV**, Toxo*
Global Mean T	50.5 (5.1)	48.7 (6.4)	47.3 (6.1)	44.8 (5.5)	HIV**, Toxo**
Executive	50.8 (6.5)	50.0 (7.1)	47.4 (7.2)	45.7 (7.6)	HIV**
Verbal	50.1 (8.5)	47.8 (7.3)	50.3 (7.5)	47.7 (6.9)	Toxo*
Working Memory	50.0 (7.5)	50.3 (11.2)	45.9 (9.6)	44.3 (9.2)	HIV**
Learning	50.7 (81)	49.0 (9.7)	46.3 (9.1)	43.2 (8.1)	HIV**, Toxo*
Memory	50.5 (7.5)	49.4 (10.5)	46.4 (9.8)	42.4 (10.2)	HIV**, Toxo**
Motor	49.5 (9.1)	48.8 (7.7)	46.4 (9.5)	44.3 (10.6)	HIV*
SIP	50.9 (6.3)	47.2 (7.4)	47.2 (7.9)	44.2 (7.0)	HIV**, Toxo**

Note: GDS = global deficit score, HIV = human immunodeficiency virus, Toxo = Toxoplasma gondii IgG antibodies, SIP = speed of information processing.

Values inside the table represent mean (standard deviation).

^*p<0.05 ,

^**p<0.01.