Table 2.
Summary of Outcomes in Reported Endocuff Studies
| Study | Country | Indications for colonoscopy, n (%) | Cecal intubation, n (%) | Mean cecal intubation time, min | Mean withdrawal time without intervention, min | Polyp detection rate, n (%) | Adenoma detection rate, n (%) | Right-sided adenoma detection, n (%) | Advanced adenomas, n (%) | Adverse events, n (%) |
|---|---|---|---|---|---|---|---|---|---|---|
| Sawatzki et al. (2015) [1] | Switzerland | Screening, 88/104 (84.6) | 103/104 (99) | 6 | 11 | 75/104 (72) | 49/104 (47) | 20/49 (41) | 14/104(13.5) | Bleeding (after polypectomy), 2/104 (1.9) |
| Polyp follow-up, 16/104 (15.4) | Abdominal pain, 2/104(1.9) | |||||||||
| Anal fissure, 1/104 (0.96) | ||||||||||
| Floer et al. (2014) [2] | Germany | Screening, surveillance, diagnostic (anemia or abdominal pain) | EC, 238/249 (96) | NA | EC, 6.32 | EC, 138/249 (55.4) | EC, 87/249 (35.4) | EC, 44% | EC, 6/249 (4) | Minor mucosal lacerations: EC, 18/249 (7.3) Standard, 2/243 (0.8) |
| Standard, 229/243 (94) | Standard, 6.05 | Standard, 93/243 (38.4) | Standard, 50/243 (207) | Standard, 24% | Standard, 1/243 (1) | |||||
| Lenze et al. (2014) [3] | Germany | Screening, surveillance, tumor screening | 49/50 (98) | 6 | 6.9 | NA | 21/50 (41) | 15/36 (42) | 7/36 (19) | Minor mucosal lacerations, 15/50 (30) |
| Chin et al. (2015) [4] | California, USA | Screening, 97/236 (41) | NM | NM | NM | EC, 78.5% | EC, 44.1% | NM | For flat polyps: EC, 23.8% Standard, 12.3%; | NM |
| Diagnostic | Standard, 57.3% | Standard, 27.3% | For SSA: EC, 10.8% Standard, 4.2% | |||||||
| Van Doorn et al. (2015) [6] | The Netherlands | Polyp surveillance, FIT+screening, sympomatic and >45 years old | EC, 508/520 (98) | EC, 7 | EC, 12 | NM | EC, 53.5% | NM | NM | NM |
| Standard, 518/525 (99) | Standard, 8.3 | Standard, 13 | Standard, 52.7% | |||||||
| Marsano et al. (2014) [7] | Not reported | Screening | NM | NM | NM | EC, 1.31/patient | EC, 46.6% | EC, 32.1% | NM | NM |
| Standard, 0.82/ patient | Standard, 30% | Standard, 18.3% | ||||||||
| Biecker et al. (2015) [8] | Germany | Screening, surveillance | 486/498 (97.6) | NM | NM | EC, 137/245 (56) | EC, 87/240 (36) | NM | 24/244 (9.8) | Minor mucosal lacerations: EC, 9/245 (4) Standard, 2/253 (1); |
| Anemia or abdominal pain | Standard, 106/253 (42) | Standard, 69/249 (28) | Loss of cuff: EC, 6/245 (2.5) |
EC, Endocuff; Standard, standard colonoscopy technique; NA, not available; NM, not mentioned; SSA, sessile serrated adenoma; FIT, fecal immunochemical testing.