TABLE 5.
Sensitivity, specificity, and agreement of three LD WB tests and the C6 ELISA for the BBI and CDC performance panelsa
Ig and test | Relative sensitivity (%) | Relative specificity (%) | Overall agreement (%) |
---|---|---|---|
IgG | |||
Marblot | 85 (89/83) | 97 (100/96) | 91 (93/90) |
Virablot | 85 (89/83) | 90 (100/88) | 88 (93/86) |
BBI WB | 81 (89/78) | 97 (100/96) | 89 (93/88) |
IgM | |||
Marblot | 62 (43/68) | 97 (88/100) | 81 (67/86) |
Virablot | 85 (86/84) | 77 (88/74) | 81 (87/79) |
BBI WB | 77 (71/79) | 100 (100/100) | 89 (87/90) |
IgG/IgM | |||
C6 ELISA | 100 (100/100) | 73 (100/69) | 93 (100/90) |
Data are presented as BBI + CDC (BBI/CDC), where BBI indicates percentages for the BBI mixed-titer performance panel and CDC indicates percentages for the CDC LD evaluation panel.