TABLE 5.
Comparison of reported CD4 reference values from populations and technology used
| Country (reference) | Population description | No. of subjects | CD4+ lymphocyte count (no. of cells/mm3)
|
Technology used | |||
|---|---|---|---|---|---|---|---|
| Mean | SD | Median | 2.5th-97.5th percentile rangea | ||||
| Botswana (present study) | ANC and STI Sentinel Surveillance participants | 251 | 626 | 208 | 599 | 275-1,114 | FACSCount |
| Botswana (present study) | Blood donors | 437 | 759 | 245 | 726 | 366-1,318 | FACSCount |
| Tanzania (16) | Local population near hospital | 147 | 980b | 310 | 968 | 372-1,588 | FACSCount |
| Cameroon (35) | Healthy visitors or guardians at hospital | 203 | 980c | 350-1,610 | FACSCount | ||
| Uganda (19) | Visitors to AIDS information center | 183 | 1,256c | 559-2,333 | FACScan | ||
| Ethiopia (17) | Factory workers | 142 | 775c | 225 | 761 | 366-1,235 | FACScan |
| The Netherlands (17) | 1,356 | 993b | 319 | 950 | 509-1,761 | FACScan | |
| Central African Republic (23) | |||||||
| Male | 68 | 927 | 349 | 851 | 380-1,617 | FACS Calibur | |
| Female | 82 | 940 | 291 | 912 | 386-1,454 | FACS Calibur | |
a
The 95th percentile ranges are presented for all but the Tanzanian and Cameroonian populations. For the Tanzanian study we estimated the 2.5th to 97.5th percentile using the mean ± 1.96·standard deviation. The 2.5th to 97.5th percentile range was not available for the Cameroonian study, so the range is presented.
b
Comparison by gender was not reported.
c
Women were reported to have higher values than men.