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. 2016 Dec 12;11(12):e0161920. doi: 10.1371/journal.pone.0161920

Fig 3. Histogram representing the mean Sphingosine‐1‐Phosphate Phosphatase 1 activity (ratio SGPP1) in different groups.

Fig 3

Sphingolipid metabolism is decreased in HIV patients compared to healthy controls (T Test = 0.012128) particularly in the INR group after antiretroviral treatment (arrow) as demonstrated by the ANOVA analysis of SGPP1 activity (p = 2.5266E-7, -log10(p) = 6.5975, FDR = 2.8123E-6). Y Axis is depicting micro molar plasma concentrations. Cont = controls; A1 and A2 are Elite controlers during recent infection and after one year of enrollment; B1 and B2 = Rapid Progressors during recent infection and after one year of enrollment; C1 and C2 = Immunologic Responders before treatment and after one year of treatment, D1 and D2 = INR before treatment and after one year of treatment.