FIG. 1.

Anti-RTF antibody-induced increased apoptosis in lymphocytes from HIV-positive individuals compared to those from healthy control individuals. Lymphocytes from seven HIV-positive individuals and seven healthy donors (uninfected) were incubated for 24 h either with the isotype control (Iso) or with monoclonal (anti-RTF) antibody 2C1. These were then analyzed for apoptosis by incubating them with annexin V-FITC and determination of the level of annexin V binding by flow cytometry on a Facscalibur (BD) flow cytometer. All values at the top indicate the percentage of annexin V binding for each population. The difference between the healthy and HIV-positive populations was judged to be significant if the P value was <0.001 by Student's t test.