Table 1.
List of the different genetically selected alcohol-preferring and nonpreferring lines available
Rat line | Predictive | Face | Construct | Notes |
---|---|---|---|---|
UChB/UChA | NA | + | +++ | Not enough information to evaluate its predictive value. |
AA/ANA | ++ | ++ | + | Little data are available to evaluate the construct validity of this rat line |
P/NP | ++ | +++ | +++ | The only line shown to voluntarily drink alcohol to intoxication |
sP/sNP | ++ | ++ | ++ | Alcohol preference was co-segregated with heightened anxiety and depressive-like traits |
HAD/LAD | ++ | ++ | ++ | Best genetic criteria for line selection |
msP | +++ | ++ | +++ | Nonpreferring line is not available. The msP showed the highest predictive validity |
Not available (NA), acceptable (+), good (++); very good (+++)