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. 2004 Aug 24;4:54. doi: 10.1186/1471-2407-4-54

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Copyright © 2004 Bougras et al; licensee BioMed Central Ltd.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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A. Growth of pCMV, Bcl-2 and Bax clones in BDIX syngenic rats. 10⁵cells from each clone were injected ic and rat survival was quantified using a Kaplan-Meier analysis. The curve illustrated is representative of 3 independent experiments. Each point represents the mean growth of 6 rats (3 rats per clone). B. The macroscopic observation of the tumors induced by the ic injection of huBcl-2, pCMV and huBax A15A5 cells into rat brains. Rat brains were stained with hematoxylin. C. Subcutaneous growth was followed by measuring the tumoral volume every 10 days after the injection of the cells. The curve illustrated is representative of 3 independent experiments. Each point represents the mean growth of 6 rats (3 rats per clone).