Table 3. Major and clinically relevant non-major risk factors for stroke and thromboembolism in non-valvular AF [11].

TIA: transient ischemic attack; LV: left ventricular; EF: ejection fraction

Major risk factors	Clinically relevant non-major risk factors
Prior stroke or TIA or thromboembolism	Heart failure or moderate to severe LV dysfunction (LV EF ≤ 40%)
Age ≥ 75 years	Hypertension
Mitral stenosis or prosthetic heart valves	Diabetes mellitus Female sex Age 65-74 years Vascular disease (prior myocardial infarction, peripheral artery disease, complex aortic plaque)