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IH in 20 mM Na+i requires phosphorylation and ATP binding. (A) Recording from a patch at −50 mV on which ATP (10 μM and 4 mM) and AMPPNP (1 mM) were applied as indicated. (B) Average current induced by 4 mM ATP, 10 μM ATP, 1 mM AMPPNP, and 10 μM ATP + 1 mM AMPPNP; data from three patches, normalized to IH at −140 mV in 4 mM MgATP. To see this figure in color, go online.
