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. 2016 Dec 6;111(11):2377–2386. doi: 10.1016/j.bpj.2016.10.023

Figure 1.

Figure 1

(A) MRE at 222 nm (dashed lines) and the storage modulus (G′) (solid lines) were measured from 4°C to 60°C for Telo-EPC in AcA versus neutral PBS buffers. Changes in MRE coincide with G′ upon fibrillogenesis and denaturation in neutral conditions. (B) A similar coincidence of MRE and G′ was observed for additional type-I collagen variants capable of self-assembly. (C) Telo-ABM, Atelo-ABM, and RT collagen in acidic conditions, and Telo-EPC in 1 M glycerol and PBS were incapable of self-assembly via rheology, and demonstrated only one transition from triple helix to a denatured state. To see this figure in color, go online.