Table 1.
Univariate (U) and multivariate (M) analysis of correlation between textural features and clinical scores in the More affected caudate.
| Parameters | p-values |
|||||||
|---|---|---|---|---|---|---|---|---|
| UPDRS III |
DD-diag. |
DD-sympt. |
MoCA |
|||||
| U | M | U | M | U | M | U | M | |
| Conventional | 0.94a | 0.88a | 0.34a | 0.96a | ||||
| Entropy | 0.0092 | 0.0027 | – | 0.0053 | ||||
| Homogeneity | < 0.001 | < 0.001 | 0.019b | 0.019 | – | |||
| Agreement | < 0.001 | < 0.001 | 0.0012 | 0.029b | – | |||
| Dissimilarity | 0.0022 | < 0.001 | 0.021b | – | ||||
| Contrast | 0.0085 | < 0.001 | < 0.001 | 0.040b | – | |||
| Energy | 0.031b | 0.037b | – | 0.041b | ||||
| MaxProbability | 0.029b | – | – | – | ||||
| SumMean | – | – | – | 0.029b | ||||
| Correlation | – | – | – | 0.0021 | ||||
| Variance | – | – | – | < 0.001 | < 0.001 | |||
| Cluster Tend. | – | – | – | 0.0034 | ||||
| Age | – | – | – | – | 0.012 | |||
Notes:
(1) Two other Haralick features (cluster shade, inverse variance) were also included in the analyses, but had insignificant contributions, and thus are not shown in this table.
(2) We report p-values in the table, while those in univariate analysis that become non-significant after correction for multiple testing (FDR) are indicated using b (see below).
a
p-Values for conventional normalized mean uptake were insignificant.
b
p-Value < 0.05 but not significant after correction for multiple testing (p-values > 0.05 are not shown except for conventional analysis).