Table 3.
Results of linear meta-regression of VBA studies of illness duration vs HCs.
Peak region | Change of FA | x | y | z | Z | p | Voxels |
---|---|---|---|---|---|---|---|
Superior longitudinal fasciculus | + | − 30 | − 48 | 50 | 1.43 | 0.0001 | 138 |
Corticospinal tract | + | 18 | − 26 | 64 | 1.33 | 0.0003 | 134 |
Forceps minor | + | − 20 | 54 | 18 | 1.42 | 0.0002 | 128 |
Forceps major | + | − 4 | − 80 | 22 | 1.45 | 0.0001 | 99 |
Anterior thalamic radiation | + | − 14 | 18 | 8 | 1.15 | 0.0012 | 109 |
Forceps major | + | 24 | − 80 | 30 | 1.26 | 0.0006 | 92 |
Corticospinal tract | + | 6 | − 46 | 64 | 1.45 | < 0.0001 | 75 |
Forceps major | + | − 34 | − 80 | 30 | 1.25 | 0.0007 | 82 |
Forceps major | + | 4 | − 80 | 24 | 1.32 | 0.0004 | 59 |
Superior corona radiata | − | − 20 | − 10 | 50 | − 2.06 | 0.0001 | 285 |
Uncinate fasciculus | − | − 24 | 34 | − 8 | − 1.26 | 0.0021 | 113 |
Inferior frontooccipital fasciculus | − | − 32 | − 30 | 14 | − 1.30 | 0.0018 | 72 |
Cingulum | − | − 8 | 12 | 36 | − 1.48 | 0.0010 | 66 |
Superior longitudinal fasciculus | − | − 48 | − 40 | 40 | − 1.30 | 0.0018 | 53 |
Cingulum | − | 8 | 18 | 36 | − 1.20 | 0.0025 | 35 |
Forceps major | − | − 18 | − 80 | 4 | − 1.10 | 0.0035 | 17 |
Note. FA is increased or decreased with longer illness duration.