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. 2016 Oct 22;12:1035–1043. doi: 10.1016/j.nicl.2016.10.014

Table 2.

Volume of subcortical structures.

Healthy controls sALS C9 + (all) C9 + subtypes
Asymp. ALS bvFTD ALS-FTD
Cerebellum 8.65 ± 0.77 8.28 ± 0.91 8.46 ± 0.91 9.22 ± 0.74 8.64 ± 0.72 7.94 ± 0.36 7.53 ± 0.65
Thalamus 0.98 ± 0.11 0.91 ± 0.10 0.88 ± 0.12a 1.01 ± 0.08 0.90 ± 0.07 0.76 ± 0.09a 0.77 ± 0.09a
Caudate 0.50 ± 0.06 0.51 ± 0.06 0.47 ± 0.08 0.49 ± 0.07 0.52 ± 0.07 0.38 ± 0.07 0.41 ± 0.05
Putamen 0.72 ± 0.10 0.70 ± 0.11 0.67 ± 0.15 0.78 ± 0.09 0.72 ± 0.11 0.51 ± 0.12 0.53 ± 0.10
Pallidum 0.20 ± 0.03 0.21 ± 0.03 0.19 ± 0.04 0.21 ± 0.03 0.21 ± 0.03 0.14 ± 0.02 0.15 ± 0.03

Volumes are expressed as % of total intracranial volumes. sALS = sporadic ALS, Asymp = C9 + asymptomatic carriers.

a

Less than controls, p < 0.05, Dunnett's test, corrected for multiple comparisons.