. 2016 May 6;12:976–989. doi: 10.1016/j.nicl.2016.05.002

Table 2.

Left MTLE-HS group voxel-based analysis.

¹⁸F-FDG-PET hypometabolism							Decreased fractional anisotropy (FA)							Increased mean diffusivity (MD)
Anatomical region	Cluster size (mm³)	Cluster level p corrected	MNI coordinates			t statistic	Anatomical region	Cluster size (mm³)	Cluster level p corrected	MNI coordinates			t statistic	Anatomical region	Cluster size (mm³)	Cluster level p corrected	MNI coordinates			t statistic
Anatomical region	Cluster size (mm³)	Cluster level p corrected	x	y	z	t statistic	Anatomical region	Cluster size (mm³)	Cluster level p corrected	x	y	z	t statistic	Anatomical region	Cluster size (mm³)	Cluster level p corrected	x	y	z	t statistic
L inf F g (opercular)	1325	0.05(FWE)	− 50	32	14	30.61	L SLF (F)/forceps minor	24 1457	0.05(FWE) 0.001	− 54	12	− 4	20.08	L SLF (F)/forceps minor	1250	0.05(FWE)	− 44	32	− 12	13.75
L Temporal (ant & mid)	4260	0.05(FWE)	− 58	6	− 26	30.52	L ILF	828	0.05(FWE)	− 40	16	30	13.54	L ILF	247	0.001	− 48	− 2	36	10.73
L Insula	648	0.05 (FWE)	32	18	2	28.35	L EC	78	0.05(FWE)	− 32	60	39	14.52	L EC	89	0.001	− 20	22	12	9.54
L Angular g/Lat occipital	612	0.05(FWE)	− 58	− 64	32	20.21	L SLF/IFL	181	0.001	− 40	− 62	12	8.27	L SLF/IFL	218	0.001	− 34	− 24	− 10	7.65
R Precentral g	574	0.05(FWE)	32	− 24	52	16.06	Post corona radiata/pyramidal tract	118	0.001	28	− 70	28	9.77	R pyramidal tract	134	0.001	10	− 36	54	7.22
R inf F g (opercular)	59	0.05(FWE)	58	34	14	15.29	R Unc	477	0.05(FWE)	18	26	− 4	12.76	R Unc	289	0.001	18	30	− 6	7.83
L Precentral g	621	0.05(FWE)	− 52	− 6	48	11.84	L SLF/pyramal tract	879	0.001	− 42	− 44	36	9.23	L SLF/pyramidal tract	461	0.001	− 18	− 10	72	10.97
L Orbito-frontal	71	0.05(FWE)	− 24	40	− 24	11.18	L Unc	136	0.05(FWE)	26	4	− 4	14.89	L Unc	65	0.001	− 18	36	− 4	9.25
Brainstem	1400	0.001	4	− 26	− 12	10.66
L Thalamus	681	0.05(FEW)	− 18	0	2	11.28
R Thalamus	248	0.001	4	− 26	− 4	9.66
L occipital pole	183	0.001	− 34	− 94	− 8	9.51	L IFO/ILF/forceps major	241	0.001	− 28	− 94	− 14	8.27	L IFO/ILF/forceps major	104	0.001	− 32	− 78	0	7.67
L mid & post Cing	109	0.001	− 6	− 52	24	8.69	L Cing/CC (Splenium)/F. Major	1554	0.05(FWE)	− 20	30	2	12.40	L Cing/CC (Splenium)/forceps major	737	0.001	0	− 38	22	7.28
L sup F g	142	0.001	− 6	60	32	8.34	Forceps minor	374	0.001	0	− 38	22	7.27	Forceps minor	159	0.001	− 18	32	16	5.75
R ant Temporal	83	0.001	62	4	− 26	8.00	R ILF	131	0.001	56	− 12	− 26	11.45
R inf F	54	0.001	42	56	12	7.39	R SLF	77	0.001	54	4	− 14	10.61	R SLF/forceps minor	859	0.001	20	32	4	6.75
L Basal Ganglia (pallidum)	681	0.001	− 18	0	2	11.28
							R post Cing	174	0.001	16	− 46	40	9.68	R post Cing	79	0.001	12	− 40	30	5.25
							R CC/forceps major	79	0.001	24	− 82	20	9.24	R CC/forceps major	65	0.001	4	− 42	14	5.43

L, left; R, right; Inf, inferior; Lat, lateral; Ant, anterior; Post, posterior; Mid, middle; F, frontal; G, gyrus; T-O: temporo-occipital; Prec, precuneus; Cing, cingulum; EC, external capsule; CC, corpus callosum; Unc, Uncinate fasciculus; IFO: inferior fronto-occipital fasciculus; SLF, superior longitudinal fasciculus; ILF, inferior longitudinal fasciculus; FWE: family-wise error; MTLE, mesial temporal lobe epilepsy; HS, hippocampal sclerosis; MNI, Montreal Neurological Institute and Hospital.