Skip to main content
. Author manuscript; available in PMC: 2017 Oct 10.
Published in final edited form as: Angew Chem Int Ed Engl. 2016 Oct 10;55(42):13155–13158. doi: 10.1002/anie.201607443

Figure 1.

Figure 1

(A) PLD physiologically catalyzes hydrolysis of phosphatidylcholine to form PA (top) and can also mediate transphosphatidylation reactions with short-chain primary alcohols (e.g., butanol) to form phosphatidyl alcohols. (B) Two-step approach to image PLD-mediated PA synthesis. Cells are treated with alkynols, resulting in PLD-mediated formation of phosphatidyl alkynols, followed by CuAAC labeling with an azido fluorophore to enable visualization or quantification.