Table 1. Top 30 Upregulated Genes in the vhl-1 versus Wild-Type Microarray Comparison and Confirmation of Selected Genes by RNase Protection Assays.

Confirmation of selected genes: Y, reproducible upregulation of gene in vhl-1/wild-type worms as confirmed by RNase protection assays; N, no reproducible upregulation of gene as tested by RNase protection assays; —, not determined. Gene name refers to the three-letter gene name where available and open reading frame name (WormBase); details of name changes and primers in arrays are from http://worm-chip.stanford.edu/pcr.all_primers.plus_gels.4–10-02.txt. Description is the predicted protein, annotated by Proteome/Incyte; —, protein of unknown function. Microarrays and RNase protection assays were performed using worms cultured under normoxic conditions