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. 2016 Dec 12;18:292. doi: 10.1186/s13075-016-1183-y

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Differential inflammatory response in juvenile (J1, J2) and adult chondrocytes (A1, A2) upon IL-1ß stimulation (10 ng/mL) upon gene expression of inflammatory genes (IL-6 and CCL2) (a), catabolic genes (MMP3 and ADAMTS4) (b) and chondrocyte regulatory genes (COL2A and SOX9) (c); *p < 0.01. Gene expression is relative to control in the absence of IL-1ß for each respective gene