Table 2. Serum biochemical data for male and female rats intragastrically administered CMLA for 14 days.
Parameter | Sex | Normal | MDLA | MDLA |
---|---|---|---|---|
0.5% CMC | 500 mg/kg | 1000 mg/kg | ||
Sodium (mmol/L) | Male | 149.75 ± 2.9 | 151.5 ± 1.6 | 150.75 ± 1.4 |
Female | 149.73 ± 0.71 | 152 ± 3.2 | 151.5 ± 0.58 | |
Potassium (mmol/L) | Male | 5.48 ± 0.23 | 6 ± 1.7 | 6.17 ± 1.4 |
Female | 5.21 ± 0.24 | 5.5 ± 0.1 | 5.45 ± 0.3 | |
Chloride (mmol/L) | Male | 114.85 ± 2.9 | 114.5 ± 1.8 | 113.75 ± 3.1 |
Female | 111.3 ± 2.1 | 112.3 ± 1.6 | 112.5 ± 4.8 | |
Carbon dioxide (mmol/L) | Male | 18.52 ± 3.6 | 19.72 ± 2.2 | 19.3 ± 2.5 |
Female | 18.45 ± 1.7 | 19 ± 3.2 | 18.1 ± 1.1 | |
Anion gap (mmol/L) | Male | 21 ± 0.52 | 22.25 ± 1.3 | 22.5 ± 2.9 |
Female | 22.8 ± 0.2 | 22.5 ± 3.4 | 22.8 ± 2.5 | |
Urea nitrogen (mmol/L) | Male | 9.03 ± 3.1 | 9.83 ± 0.7 | 10.3 ± 0.5 |
Female | 9.32 ± 2.8 | 9.2 ± 1.7 | 9.8 ± 3.3 | |
Creatinine (umol/L) | Male | 23.61 ± 4.5 | 24 ± 3.2 | 23 ± 3.9 |
Female | 26.01 ± 4.1 | 23.5 ± 1.8 | 23 ± 1.5 | |
Total protein (g/L) | Male | 57.5 ± 5.6 | 55.5 ± 2.8 | 58.75 ± 1.2 |
Female | 57.4 ± 0.9 | 56.5 ± 1.6 | 57.3 ± 0.2 | |
Albumin (g/L) | Male | 13.3 ± 2.7 | 14.25 ± 1.9 | 14 ± 1.8 |
Female | 12.5 ± 1.7 | 13.8 ± 1.6 | 12.3 ± 1.3 | |
Globulin (g/L) | Male | 44.42 ± 4.7 | 45 ± 3.1 | 44.75 ± 2.6 |
Female | 43.5 ± 2.7 | 43.8 ± 3.2 | 43.3 ± 3.9 | |
Total bilirubin (umol/L) | Male | 2.92 ± 0.2 | 2.5 ± 0.1 | 3 ± 0.9 |
Female | 2.5 ± 0.4 | 2.5 ± 0.1 | 2.5 ± 0.7 | |
Alkaline phosphatase (IU/L) | Male | 92.5 ± 8.2 | 93.25 ± 6.1 | 92.25 ± 3.3 |
Female | 85 ± 3.9 | 85 ± 4.1 | 86.3 ± 5.8 | |
Alanine aminotransferase (IU/L) | Male | 53.56 ± 4.8 | 52.75 ± 4.6 | 54.75 ± 5.2 |
Female | 51.3 ± 5.1 | 50.5 ± 5.8 | 50.3 ± 3.7 | |
Aspartate Aminotransferase (IU/L) | Male | 191 ± 9.5 | 192.3 ± 11.7 | 190.5 ± 12.4 |
Female | 199.4 ± 6.9 | 201 ± 9.2 | 200 ± 14.7 |
Values are expressed as mean ± SEM. There are no significant differences between groups significant value at P < 0.05.