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. 2016 Dec 13;6:38717. doi: 10.1038/srep38717

Figure 1. Loss of IL-17 restores normal secretory function of the salivary glands.

Figure 1

Stimulated saliva were collected and measured. (A) Restored normal saliva flow of male and female mice. The saliva flow rate for males, females and males with females (SFR ± SEM, presented as μL/gram/10 min) is shown from 4–28 weeks of age (B6 F, n = 8; B6 M, n = 7; B6.Il17−/− F, n = 5; B6.Il17−/− M, n = 5; B6.NOD-Aec1Aec2 F, n = 7; B6.NOD-Aec1Aec2 M, n = 6; B6.NOD-Aec1Aec2.Il17−/− F, n = 5; B6.NOD-Aec1Aec2.Il17−/− M, n = 10) for males. The statistical differences were determined using one-way ANOVA where **p < 0.005, ***p < 0.001 and ****p < 0.0001. (B) Normal saliva flow at advanced age in males and females. The percentage of the loss of SFR between the 4-week and 28-week time points is displayed ± SEM for males, females and males with females. The statistical differences were determined using one-tailed unpaired t-test with Welch’s correction (NS: not significant, *p < 0.05, **p < 0.01, and ***p < 0.001).