Figure 1. Viability of recombinant viruses with genomic patterns A to F.

The genomic organization of the enterovirus genome is shown at the top. The name of the recombinant viruses is indicated on the left-hand side: the letter indicates the genomic pattern and the number indicates the non-polio enterovirus strain used to construct the chimeric genome. On the right-hand side, a green tick indicates the viability of the virus recovered after the transfection of HEp-2c cells with the recombinant genome, whereas a red cross indicates that no viable virus was obtained from the recombinant genome under the same conditions, even after two blind passages.