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. 2016 Dec 12;17:527. doi: 10.1186/s12859-016-1395-9

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 12 — The connected subgraph of hsa05200 and mmu05200 pathways in human and mouse from the PROPER algorithm, with conserved interactions in both species. This connected subgraph has 37 nodes and 42 edges. The PINALOG algorithm returns the second largest connected subgraph. The rectangular nodes and solid edges are the proteins and interactions among them that are found only by the PROPER algorithm