Table 1.
Demographic and clinical characteristics of patients with positive isolates for XDRAB
| Variable | No of patients (%) n = 8 |
|---|---|
| Age (years), mean ± SD | 64.5 ± 14.7 |
| Male % | 4 (50) |
| Intrinsic Risk Factors | |
| Tabagism | 3 (37.5) |
| Diabetes Mellitus | 2 (25) |
| Chronic Obstructive Pulmonary Disease | 2 (25) |
| Previous hospitalization | 2 (25) |
| Chronic kidney disease | 1 (12.5) |
| Malignancy | 1 (12.5) |
| Politrauma | 1 (12.5) |
| Use of steroid | 7 (87.5) |
| Diagnoses upon admission | |
| Coronary Artery Disease | 2 (25) |
| Respiratory Failure | 1 (12.5) |
| Pulmonary Embolism | 1 (12.5) |
| Pneumonia | 1 (12.5) |
| Cancer | 1 (12.5) |
| Shock | 1 (12.5) |
| Fracture/Politrauma | 1 (12.5) |
| Site of isolates | |
| Bronchoalveolar lavage | 6 (37.5) |
| Endotracheal aspirate | 4 (25) |
| Central venous blood | 2 (12.5) |
| Sputum culture | 2 (12.5) |
| Peripheral venous blood | 1 (6.25) |
| Rectal swab | 1 (6.25) |
| Device | |
| Endotracheal tube | 8 (100) |
| Central venous catheter | 8 (100) |
| Pleural dreinage | 2 (25) |
| Total Parental Nutrition | 5 (62.5) |
| Previous use of antibiotic in the preceding 90 days | |
| β-lactam | 1 (12.5) |
| β-lactam plus another antibiotic | 1 (12.5) |
| β-lactam plus at least two other categories of antibiotics | 6 (75) |
| Hospital stay before acquisition of XDRAB (days) | 8.3 ± 8.8 |
| ICU stay before acquisition of XDRAB (days) | 9.4 ± 8.8 |
| Clinical significance | |
| Ventilator associated Pneumonia | 6 (75) |
| Central venous catheter infection | 2 (25) |
| Outcome | |
| In-hospital mortality | 4 (50) |