Case study 2: Hind and colleagues [45] use qualitative research to explore the acceptability of computerised cognitive behavioural therapy for the treatment of depression in people with multiple sclerosis. This is undertaken in the context of a wider study which included a pilot randomised controlled trial.

Research question: In the introduction of the paper the authors reference previous research which identifies the importance of exploring whether an intervention engages specific target groups, and the importance of understanding the acceptability of computerised cognitive behaviour therapy.

Design and data collection: A patient representative was a member of the research team and was involved in the design and conduct of the study. Data collection for the qualitative study consisted of face-to-face semi-structured interviews with 17 patients who had used one of two computerised cognitive behaviour therapy packages. There was also brief weekly written feedback from patients and brief telephone interviews at the start of the intervention to identify immediate problems.

Analysis: Framework analysis was used and is referenced. A patient representative participated in the analysis of the data.

Reporting: Although not mentioned in the title of the paper, or the abstract, the authors are clear in the introduction that this paper that the qualitative research was undertaken in the same study as a pilot trial. The qualitative findings are described in detail using quotes from participants. The conclusions relate to the intervention - that computerised cognitive behaviour therapy packages would need to be adapted for people with chronic physical disease - but are not explicit about the implications for a full randomised controlled trial.