Table 1.

Risk factors for being diagnosed with HSV-2 at baseline

Variable	Overall number (% of group)	Univariate analysis		Multivariate analysis
	N = 2236	Odds ratio (95% CI)	p value	Odds ratio (95% CI)	p value
Age*
<23	660 (29.5)	1		1
23–27	484 (21.6)	1.76 (1.39–2.23)	0.001	1.75 (1.37–2.23)	0.001
28–37	564 (25.2)	3.40 (2.67–4.33)	0.001	3.24 (2.50–4.20)	0.001
38+	528 (23.6)	6.72 (5.06–8.92)	0.001	6.08 (4.44–8.32)	0.001
Employed/income
Yes	1842 (82.4)	1.0		1.0
No	394 (17.6)	1.85 (1.43–2.36)	0.001	1.43 (1.10–1.87)	0.008
Religion
Other	1346 (60.2)	1.0		1.0
Christian	890 (39.8)	1.09 (0.91–1.30)	0.334	–	–
Education
≥High school	1550 (69.3)	1.0
<High school	686 (30.7)	1.78 (1.47–2.14)	0.001	1.24 (1.01–1.52)	0.037
Age at first sex act (years)
>15	2123 (94.9)	1.0
<15	113 (5.1)	1.33 (0.88–2.02)	0.175	–	–
Sex acts per week**
<3	1282 (57.3)	1.0
3+	954 (42.7)	0.99 (0.83–1.18)	0.934	–	–
Sexual partners
1 partner	606 (27.1)	1.0
2 + partners	1630 (72.9)	1.27 (1.06–1.55)	0.011	–	–
STI
C. trachomatis	244 (10.9)	1.07 (0.81–1.42)	0.624	1.51 (1.11–2.04)	0.007
N. gonorrhea	71 (3.2)	1.89 (1.07–3.31)	0.027	2.37 (1.31–4.29)	0.004
Syphilis	56 (2.5)	4.62 (1.97–10.81)	0.001	2.88 (1.20–6.94)	0.018
T. vaginalis	200 (8.9)	1.51 (1.09–2.09)	0.013	1.50 (1.06–2.12)	0.024
Contraception
None	185 (8.3)	1.0
Othera	228 (10.2)	1.75 (1.09–2.81)	0.021	–	–
Hormonal	1196 (53.49)	0.63 (0.44–0.89)	0.008	–	–
Condoms	627 (28.0)	0.52 (0.36–0.74)	0.001	–	–

CI confidence interval

^aIncludes tubal ligation, intrauterine devices and traditional methods

* Median (IQR) = 27 (23–37); p value for rank test was < 0.001

** Median (IQR) = 3 (2–4); p value for rank test was 0.511