Table 1.
Modifiable risk factors and conditions identified by In-MINDD as potentially increasing or reducing dementia risk (adapted from [12])
| Risk/protective factor | Relative risk from published literature | Weight applied to factor for LIBRA global score |
|---|---|---|
| Low/moderate alcohol consumption | 0.74 | −1.0 |
| Coronary heart disease | 1.36 | +1.0 |
| Physical inactivity | 1.39 | +1.1 |
| Renal dysfunction | 1.39 | +1.1 |
| Diabetes | 1.47 | +1.3 |
| Raised cholesterol level | 1.54 | +1.4 |
| Smoking | 1.59 | +1.5 |
| (Midlife) obesity | 1.60 | +1.6 |
| (Midlife) hypertension | 1.61 | +1.6 |
| Mediterranean diet | 0.60 | −1.7 |
| Depression | 1.85 | +2.1 |
| Cognitive activity | 0.38 | −3.2 |