Table 3.
Comorbidity and health care consumption 2006–2010, divided by sex and bDMARDs
| Women, bDMARDs (n = 880) | Women, no bDMARDs (n = 4559) | P-value | Men, bDMARDs (n = 257) | Men, no bDMARDs (n = 1626) | P-value | |
|---|---|---|---|---|---|---|
| Age, years | 58.7 ± 12.4 | 65.6 ± 15.6 | <0.001 | 59.7 ± 12.0 | 67.6 ± 13.5 | <0.001 |
| Comorbid conditions, n (%) | ||||||
| Diabetes mellitus | 62 (7.0) | 478 (10.5) | 0.002 | 31 (12.1) | 237 (14.6) | 0.284 |
| Hypertension | 268 (30.5) | 1932 (42.4) | <0.001 | 91 (35.4) | 730 (44.9) | 0.004 |
| Ischemic heart disease | 48 (5.5) | 591 (13.0) | <0.001 | 44 (17.1) | 356 (21.9) | 0.082 |
| Heart failure | 21 (2.4) | 416 (9.1) | <0.001 | 12 (4.7) | 240 (14.8) | <0.001 |
| Valvular disease | 15 (1.7) | 151 (3.3) | 0.011 | 8 (3.1) | 67 (4.1) | 0.443 |
| Atrial fibrillation or flutter | 34 (3.9) | 396 (8.7) | <0.001 | 16 (6.2) | 249 (15.3) | <0.001 |
| Cerebrovascular disease | 30 (3.4) | 392 (8.6) | <0.001 | 15 (5.8) | 182 (11.2) | 0.009 |
| Venous thromboembolic disease | 41 (4.7) | 260 (5.7) | 0.215 | 6 (2.3) | 103 (6.3) | 0.011 |
| Chronic respiratory disease | 91 (10.3) | 702 (15.4) | <0.001 | 39 (15.2) | 282 (17.3) | 0.390 |
| Chronic renal insufficiency | 6 (0.7) | 90 (2.0) | 0.008 | 2 (0.8) | 53 (3.3) | 0.028 |
| Depression | 87 (9.9) | 614 (13.5) | 0.004 | 17 (6.6) | 124 (7.6) | 0.567 |
| Malignancy | 61 (6.9) | 597 (13.1) | <0.001 | 26 (10.1) | 324 (19.9) | <0.001 |
| Infections | 663 (75.3) | 3153 (69.2) | <0.001 | 172 (66.9) | 1060 (65.2) | 0.587 |
| Pneumonia Sepsis |
107 (12.2) 15 (1.7) |
676 (14.8) 114 (2.5) |
0.039 0.155 |
38 (14.8) 5 (1.9) |
278 (17.1) 73 (4.5) |
0.357 0.057 |
| Fractures (sites related to osteoporosis) | 59 (6.7) | 402 (8.8) | 0.039 | 6 (2.3) | 74 (4.6) | 0.102 |
| Prosthetic surgery | ||||||
| Hip Knee |
33 (3.8) 29 (3.3) |
186 (4.1) 165 (3.6) |
0.649 0.635 |
10 (3.9) 9 (3.5) |
67 (4.1) 48 (3.0) |
0.863 0.633 |
| Health care consumption | ||||||
| Patients hospitalizeda, n (%) | 449 (51.0) | 2369 (52.0) | 0.609 | 122 (47.5) | 832 (51.2) | 0.271 |
| Number of inpatient admissionsa
Cumulative days at hospitala |
2 (1, 3) 6 (3, 13) |
2 (1, 3) 9 (3, 26) |
0.752 <0.001 |
2 (1, 3) 7 (3, 15) |
2 (1, 3) 10 (4, 26) |
0.784 0.013 |
| Outpatient visits, secondary care | 22 (15, 34) | 11 (7, 18) | <0.001 | 20 (12, 32) | 11 (7, 18) | <0.001 |
| Outpatient visits, primary care | 7 (3, 11) | 9 (5, 15) | <0.001 | 6 (3, 11) | 8 (4, 13) | <0.001 |
Data are expressed as number (%), mean ± SD or median (first, third quartile). Numbers of admissions, cumulative days at hospital or outpatient visits are calculated on patients who have been hospitalized or have been in outpatient care, respectively, and not on all patients
aHospitalizations of one day and connected to an intravenous treatment were not included