Table 1. Clinical characteristics of the subjects.
Normal (n = 46) | ICP (n = 70) | p value | |
---|---|---|---|
Maternal age (years) | 30.5 ± 3.2 | 30.2 ± 4.0 | 0.648 |
BMI of mother | 21.3 ± 2.5 | 21.8 ± 3.0 | 0.359 |
Gravidity | 1.7 (1–4) | 1.7 (1–7) | 0.473 |
Parity | 1.3 (1–2) | 1.2 (1–3) | 0.063 |
Gestational age (weeks) | 38.9 ± 1.0 | 37.6 ± 1.6 | <0.0001 |
TBA at delivery (μmol/L) | 5.8 ± 2.9 | 29.4 ± 24.1 | <0.0001 |
Birth weight (g) | 3368.6 ± 354.6 | 3056.7 ± 395.1 | <0.0001 |
Placenta weight (g) | 538.1 ± 77.4 | 488.0 ± 91.7 | <0.01 |
Apgar at 5 min | 9.98 (9–10) | 9.94 (7–10) | 0.545 |
Sex of neonate | |||
Male (%) | 18 (39.1) | 39 (55.7) | 0.081 |
Female (%) | 28 (60.9) | 31 (44.3) |
Abbreviation: ICP, intrahepatic cholestasis of pregnancy; BMI, body mass index; TBA, total bile acids. Values are given as mean ± SD, mean (range), or N (percent).