Table 1. Crystallographic data and refinement statistics of S. aureus 50S in complex with lefamulin (SA50S-lef).
| SA50S-lef | |
|---|---|
| Crystal information | |
| Space group | P6522 |
| a = b [Å] | 282.1 |
| c [Å] | 875.3 |
| α, β, γ [°] | 90, 90, 120 |
| Diffraction data statistics | |
| X-ray source (ESRF) | ID23-1 |
| Wavelength [Å] | 0.972 |
| Number of crystals | 12 |
| Resolution [Å] | 50–3.55 (3.61–3.55) |
| Observed reflections | 2606786 |
| Unique reflections | 236087 |
| Redundancy | 11.0 (9.2) |
| Completeness [%] | 95.7 (94.6) |
| <I>/<σ (I)> | 9.0 (1.71) |
| R-merge [%] | 20.9 (99.4) |
| Refinement statistics | |
| R-factor [%] | 18.69 |
| R-free (5%) [%] | 22.66 |
| rmsd bonds [Å] | 0.01 |
| rmsd angles [°] | 1.61 |
*In parentheses are the values for the highest resolution shells. Abbreviations: ESRF, European Synchrotron Radiation Facility; rmsd, root-mean-square deviation.