Skip to main content
. 2016 Dec 13;6:38999. doi: 10.1038/srep38999

Figure 2. MKP-2−/− mice develop less severe EAE then MKP-2+/+ counterparts.

Figure 2

MKP-2+/+ and MKP-2−/− mice were inmmunised as described in Materials and Methods. (A) EAE incidence in MKP-2+/+ and MKP-2−/− mice, n = 24 in each group. (B) Clinical score of EAE development in MKP-2+/+ and MKP-2−/− mice. Data show mean ± SEM of 24 mice per group from at least 4 independent experiments. *P < 0.05; **P < 0.01, ***P < 0.001. (C) H&E, CD45, CD4, CD8, CD11b and CD11c staining of spinal cords 17 days post immunisation. Images are representative of at least 12 mice per group from three independent experiments, scale bars = 100 μm.