Fig. 3.

VX-970 treatment increases the sensitivity of esophageal cancer cells to radiation in normoxic and hypoxic conditions. OE21 (A) and FLO-1 (B) cells were treated with VX-970 (50 nM) and then irradiated with the doses indicated followed by a colony survival assay. This experiment was then repeated in hypoxic conditions (<0.1% O₂) for OE21 (C) and FLO-1 (D) cells. Results shown are mean ± SEM (n = 3). Significance: Two-way ANOVA test, ^**P < 0.01,^****P < 0.0001.