Table 4. Evolution rate of 1E and 2B viruses in different domains1.
| Region | Genotype 1E | Genotype 2B |
|---|---|---|
| Whole genome | 1.04 × 10−3(95%HPD:5.02 × 10−4–1.59 × 10−3) | 1.34 × 10−3(95%HPD:2.34 × 10−4–1.56 × 10−3) |
| 5′UTR | na | na |
| NSP | 1.14 × 10−3(95%HPD:5.38 × 10−4–1.74 × 10−3) | 1.36 × 10−3(95%HPD:4.97 × 10−4–2.13 × 10–3) |
| p150 | 1.10 × 10−3(95%HPD:4.66 × 10−4–1.73 × 10−3) | 1.64 × 10−3(95%HPD:7.31 × 10−4–2.51 × 10−3) |
| MT | 2.34 × 10-2(95%HPD:2.11 × 10-7–9.50 × 10−2) | 2.55 × 10−3(95%HPD:7.58 × 10−7–8.08 × 10−3) |
| HVR-I(low BT) | 8.97 × 10−3(95%HPD:5.56 × 10−4–2.34 × 10−2) | 3.02 × 10−3(95%HPD:5.30 × 10−4–5.69 × 10−3) |
| HVR-II(low BT) | na | na |
| X-Domain (low BT) | 2.11 × 10−3(95%HPD:4.92 × 10−4–4.18 × 10−3) | 3.66 × 10−3(95%HPD:3.60 × 10−4–8.88 × 10−3) |
| Pro | 1.35 × 10−3(95%HPD:4.63 × 10−4–2.15 × 10−3) | 2.08 × 10−3(95%HPD:4.92 × 10−4–3.48 × 10−3) |
| NP | 1.49 × 10−3(95%HPD:4.67 × 10−4–2.42 × 10−3) | 1.86 × 10−3(95%HPD:7.15 × 10−4–3.02 × 10−3) |
| p90 | 1.27 × 10−3(95%HPD:5.92 × 10−4–1.97 × 10−3) | 1.02 × 10−3(95%HPD:2.81 × 10−4–1.76 ×10−3) |
| Hel | 1.63 × 10−3(95%HPD:3.25 × 10−4–3.05 × 10−3) | 1.38 × 10−3(95%HPD:1.44 × 10−4–2.66 × 10−3) |
| RdRp | 2.66 × 10−3(95%HPD:2.55 × 10−4–6.65 × 10−3) | 1.11 × 10−3(95%HPD:2.99 × 10−4–1.90 × 10−3) |
| IR | na | na |
| SP | 1.16 × 10−3(95%HPD:5.28 × 10−4–1.74 × 10−3) | 1.44 × 10−3(95%HPD:5.96 × 10−4–2.20 × 10−3) |
| C | 1.79 × 10−3(95%HPD:6.52 × 10−4–3.09 × 10−3) | 1.75 × 10−3(95%HPD:6.21 × 10−4–2.83 × 10−3) |
| E2 | 1.56 × 10−3(95%HPD:6.65 × 10−4–2.51 × 10−3) | 1.96 × 10−3(95%HPD:6.88 × 10−4–3.15 × 10−3) |
| E1 | 1.15 × 10−3(95%HPD:3.86 × 10−4–1.81 × 10−3) | 1.34 × 10−3(95%HPD:5.54 × 10−4–2.19 × 10−3) |
| 739-nt | 1.82 × 10−3(95%HPD:3.75 × 10−4–3.24 × 10−3) | 1.76 × 10−3(95%HPD:6.92 ×10−4–2.85 × 10−3) |
| 3′UTR | na | na |
1including 11 genotype 1E viruses and 10 genotype 2B viruses (see Table 1 and Supplemental Table 2); na: not available.