Table 1.
Free radicals oxidation intensity and antioxidant system activity changes in renal lithiasis
| Index | Group I | Group II | p1 | Group III | p2 |
|---|---|---|---|---|---|
| NO (μmol/ l) | 80,94 ± 1,39 | 81,42 ± 2,09 | +0,6%, p>0,05 | 104,17 ± 2,51 | +28% p<0,001 |
| DAM (μmol/ l) | 13,31 ± 0,68 | 20,57 ± 1,67 | +70%, p<0,001 | 14,65 ± 0,69 | -29%, p<0,001 |
| AGE (μg/ ml) | 550,53 ± 26,57 | 567,6 ± 33,89 | +3%, p>0,05 | 409,10 ± 24,89 | -28%, p<0,001 |
| Ceruloplasmin (μmol/ l) | 353,57 ± 11,29 | 408,3 ± 14,19 | +14%, p<0,01 | 371,91 ± 14,24 | -9%, p<0,05 |
| SOD (μmol/ s.l) | 863,88 ± 19,72 | 809,7 ± 42,22 | -7%, p<0,05 | 851,87 ± 20,09 | +5%, p ≈ 0,53 |
| Catalysis (μmol/ s.l) | 11,39 ± 1,00 | 10,77 ± 1,31 | -5%, p>0,05 | 10,63 ± 0,76 | -1%, p≈0,48 |
| GR (nmol/ s.l) | 475,77 ± 26,81 | 511,6 ± 65,61 | +8%, p>0,05 | 402,46 ± 22,41 | -21%, p≈0,74 |
| GPO (nmol/ s.l) | 549,98 ± 49,95 | 443,4 ± 58,04 | -20%, p<0,05 | 666,3 ± 114,39 | +50%, p<0,01 |
| G-S-T (nmol/ s.l) | 119,09 ± 9,09 | 106,1 ± 14,14 | -13%, p<0,05 | 81,48 ± 10,17 | -23%, p≈0,35 |
| Protein-SH groups (μmol/g prot.) | 7,58 ± 0,34 | 7,29 ± 0,62 | -6%, p<0,01 | 3,40 ± 0,21 | -53% p<0,001 |
| S-nitrosothiol (μmol/ l) | 3,84 ± 0,09 | 3,74 ± 0,12 | -3%, p>0,05 | 3,56 ± 0,13 | -5%, p≈0,22 |
| NOTE: a) Group I – control, Group II – renal lithiasis, Group III – renal lithiasis + surgical treatment; | |||||
| b) p1 - the veracity of statistical differences between group I vs. II according to Kolmogorov-Smirnov test; | |||||
| c) p2 - the veracity of statistical differences between group II vs. III according to the Wilcoxon test. |