Table 2. Summary of deaths during induction.

ID	Patient details	Comorbidities	Hepatotoxicity (grade)	Neutropenic sepsis (organism)	Haemorrhage (site)	Thrombosis/visceral ischaemia (site)	Pancreatitis	Other	PEG-ASP doses	Days from last PEG-ASP dose
1003	Age 54 years PH−	Liver cirrhosis	4	Not known					D4 and 18	19
1004	Age 46 years PH+	None		Pseudomonas aeruginosa		Acute coronary syndrome			D4	16
1011	Age 43 years PH+	None	4	Escherichia coli				Renal failure	D4 & 18	8
1021	Age 65 years PH−	None	4	Pseudomonas aeruginosa		Gastrointestinal			D4	50
1026	Age 64 years PH+	Depression	4	Pseudomonas aeruginosa					D4	20
1028	Age 38 years PH+	None		Enterococcus faecium					D4	15
1029	Age 60 years PH+	IHD	4	Escherichia coli					D4	14
1030	Age 49 years PH+	None			Pulmonary				D4	6
1039	Age 62 years PH+	None	2			Small bowel			D4	10
1043	Age 63 years PH−	Grade 4 renal failure	4	Klebsiella pneumoniae	Carotid artery puncture site				D4 and D18	43
1049	Age 56 years PH+	None	4	Pseudomonas aeruginosa					D4	11
1057	Age 57 years PH−	None	4			Small bowel			D4	20
1061	Age 54 years PH+	Paroxysmal atrial fibrillation	3				Yes	GI perforation	D4	10
1063	Age 62 years PH+	None		Coagulase-negative staph/Enterococcus faecium					D4 and D18	12
1068	Age 64 years PH+	None	4	Respiratory syncytial virus				Renal failure	D4	21
2007	Age 55 years PH−	None		Pseudomonas aeruginosa					D4 and D18	8

Abbreviations: IHD, ischaemic heart disease; PEG-ASP, pegylated asparaginase.