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. 2016 Oct 11;24(11):1926–1938. doi: 10.1038/mt.2016.160

Figure 7.

Figure 7

Circulating GDF11/8 is positively related with endothelium-dependent vasodilation in overweight subjects. (a) Circulating GDF11/8 concentrations in different quartiles of FMD levels in overweight subjects. Data were shown as mean ± SD. Analysis of variance (ANOVA) followed by LSD t-test was used to compare the differences among different groups. **P < 0.01 versus Quartile 1. (b) Correlation analysis to evaluate correlation of circulating GDF11/8 with FMD in overweight subjects. Correlation was performed using Pearson's method. (c) The changes of plasma GDF11/8 with ages in this study group. The GDF11/8 levels declined with age (P < 0.01 for trend). ANOVA followed by LSD t-test was used to compare the differences among different groups. GDF11, growth differentiation factor 11; SD, standard deviation; FMD, flow-mediated endothelium-dependent artery dilatation; LSD, least significant difference.