Figure 7.
Human HSCs differentiate into Sox10+ glial-like cells. Images were obtained from the ouabain-exposed ear of a transplanted NSG mouse. Ouabain was applied to the right ear of the transplanted mouse and cochlear tissues from control (left) and injured ear were examined 7 days later. Immunostaining for Sox10 (red) and AHA (green) in the AN of a human CD34+ cell transplanted mouse. Arrow points to the same cell in all three images. Scale bar = 7 µm.