LHY |
Various IR at the 5’UTR (IR 1, 2 and 3) |
Together, they form up to 26% total transcripts at 4°C; |
These add up to 12 uAUG (up to 31 aa uORF) |
|
Alt 3' ss Intron 1 |
12% total transcripts at 4°C; |
Adds 1 uAUG (31 aa uORF) |
|
Intron 4 retained (I4R) |
40% total transcripts at 4°C |
Creates PTC on Exon 5 |
|
Intron 8 retained (I8R) |
37% total transcripts at 4°C |
Altered C-terminus coding region |
PRR37 |
Cryptic intron E1 (-102 nt) |
20% total transcripts at 20°C |
Loss of uORF coding for 48 amino acids |
|
Intron 1 retained |
17% total transcripts at 20°C |
Adds uORF coding for 45 amino acids that overlaps functional ORF by 35 nt |
|
alt 3' ss E6 (-6 nt) |
33% total transcripts at 20°C |
Altered protein coding sequence |
|
alt 5' ss E6 (- 45 nt) and alt 3' ss E6 (-6 nt) |
24% total transcripts at 20°C |
Altered protein coding sequence |
|
alt 5' ss E6 (- 45 nt) |
76% total transcripts at 4°C |
Altered protein coding sequence |
GI |
E2 skipping and Alt 3’ ss I2 (+12 nt) |
Up to 30% total transcripts at 20°C |
Removes 3 uAUG (up to 18 aa uORF) |
|
Alt 3’ ss I2 (+12 nt) |
Up to 22% total transcripts at 20°C |
- |
|
alt 5’ ss E2 (-8 nt) and alt 3’ ss I2 (+12 nt) |
Up to 11% total transcripts at 20°C; |
- |
CO2 |
Alt 3’ ss (+68 nt) |
35% total transcripts at 20°C |
Creates PTC |