Organ System score	1	2	3	4
Respiration
PaO2/FiO2 (kPa)	40–53.3	0–39.9	0–25.2 R)	0–13.3 R)
Coagulation
Platelets x103 (mm3/L)	101–150	51–100	21–50	0–20
Liver
Bilirubin (mg/dL)	1.2–1.9	2.0–5.9	6.0–11.9	>12.0
Nervous system
Glasgow coma score	13–14	10–12	6–9	<6
Cardiovascular
Hypotension	MAP* 0–70	Dopamine ≤ 5.0 or Dobutamine (any dose)	Dopamine 5–14.9 or Epinephrine ≤ 0.1 or Norepinephrine ≤ 0.1	Dopamine ≥ 15 or Epinephrine ≤ 0.1 or Norepinephrine ≤ 0.1
Renal
Creatinine (mg/dL)	1.2–1.9	2.0–3.4	3.5–4.9	>5.0

MAP: mean arterial pressure (mmHg).

Adrenergic agents administered for at least 1 h.