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. 2016 Aug 21;5:54–64. doi: 10.1016/j.ynstr.2016.07.001

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© 2016 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 3 — Effects of social defeat stress on hippocampal dopamine- and GluA2-related function in adolescent male C57BL/6 mice. (a) Social defeat stress increased cytosolic tyrosine hydroxylase (TH), when compared to controls (^∗∗p < 0.01). (b) Similarly, social defeat stress increased cytosolic dopamine transporter (DAT) levels, when compared to controls (^∗p < 0.05). (c) No differences in synaptic dopamine-1 receptors (D1) were observed between the groups (p > 0.05). (d) Conversely, social defeat stress reduced synaptic GluA2 when compared to controls (^∗p < 0.05). (e–f) No differences in synaptic PKMζ or PKCζ were evident following social defeat stress (p > 0.05). Arbitrary units (AU). Data are presented as ratio of total protein normalized to GAPDH (mean + SEM).