Table 2.

Biochemical characteristics of the HFrEF patients with atrial fibrillation (AF) and sinus rhythm (SR) and controls.

	HFrEF-AF (n=62)	HFrEF-SR (n=68)	Controls (n=50)	P1	P2
Creatinine (mg/dl)	1.1 (0.83–1.32)	1.06 (0.79–1.39)	0.78 (0.68–0.85)	<0.001	0.694
eGFR (ml/min)	53 (43–81)	66 (41–92)	101 (53–98)	<0.001	0.328
Uric acid (mg/dl)	7.8 (6.4–9.5)	6.6 (4.8–8.8)	5.6 (4.6–6.1)	<0.001	0.014
Hs-CRP (mg/dl)	0.94 (0.23–2.72)	0.87 (0.31–3.39)	0.27 (0.08–0.54)	<0.001	0.460
Haemoglobin (g/dl)	13.0 (11.1–14.5)	12.2 (11.2–13.7)	13.7 (12.8–14.6)	0.003	0.214
Neutrophil to lymphocyte ratio	2.94 (2.24–4.32)	2.56 (1.80–3.56)	1.82 (1.45–2.49)	<0.001	0.067
Albumin (mg/dl)	3.6 (3.2–3.9)	3.6 (3.31–4.09)	4.4 (4.1–4.5)	<0.001	0.575
Total cholesterol (mg/dl)	142 (117–174)	167 (132–195)	197 (177–222)	<0.001	0.017
Triglycerides (mg/dl)	94 (80–130)	132 (88–169)	133 (90–187)	0.004	0.007
T3 (mIU/L)	2.65 (2.40–2.95)	2.76 (2.44–3.08)	3.18 (3.00–3.48)	<0.001	0.182
TSH (mIU/L)	1.21 (0.50–2.54)	1.16 (0.73–2.05)	1.17 (0.70–1.67)	0.619	0.955
NT-Pro BNP (pg/ml)	1910 (900–4030)	1040 (291–4300)	61 (25–105)	<0.001	0.102
NGAL (ng/ml)	113 (88–148)	95 (75–143)	84 (53–98)	<0.001	0.090

eGFR – estimated glomerular filtration rate; hs-CRP – high sensitive C-reactive protein; NGAL – Neutrophyil gelatinase-associated lipocalin; T3 – triiodothyronine; TSH – thyroid stimulating hormone; P1 – significance of group differences in Kruskal-Wallis test; P2 – significance of difference between HFrEF-AF and HFrEF-SR in Mann-Whitney U test.