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Caspase-3 and PARP-mediated apoptosis induced by Ag@PEI@PTX in HepG2 cells.
Notes: (A) HepG2 cells treated with Ag@PEI@PTX and caspase-3 activity were analyzed by synthetic fluorogenic substrate. (B) The expression of PARP and caspase-3 by Western blot; β-actin was used as the loading control. Bars with different characters are statistically different at P<0.05 (*) or P<0.01 (**) level.
Abbreviations: AgNPs, silver nanoparticles; PARP, poly(ADP-ribose) polymerase.
